diff --git a/net-im/weechat-matrix/files/weechat-matrix-0.3.0-ssl_set_npn_protocols.patch b/net-im/weechat-matrix/files/weechat-matrix-0.3.0-ssl_set_npn_protocols.patch
new file mode 100644
index 0000000..29cb063
--- /dev/null
+++ b/net-im/weechat-matrix/files/weechat-matrix-0.3.0-ssl_set_npn_protocols.patch
@@ -0,0 +1,27 @@
+From 4e585d5f4628e6fbeba9ec4560b440d731e076f5 Mon Sep 17 00:00:00 2001
+From: Jonas Witschel <diabonas@archlinux.org>
+Date: Sat, 11 Dec 2021 19:47:16 +0100
+Subject: [PATCH] server: remove set_npn_protocols()
+
+This function is deprecated in favour of set_alpn_protocols(), which is already
+called, and is currently broken in Python 3.10, so remove it altogether.
+---
+ matrix/server.py | 5 -----
+ 1 file changed, 5 deletions(-)
+
+diff --git a/matrix/server.py b/matrix/server.py
+index dda861e..0f34c1e 100644
+--- a/matrix/server.py
++++ b/matrix/server.py
+@@ -303,11 +303,6 @@ def __init__(self, name, config_ptr):
+         # Enable http2 negotiation on the ssl context.
+         self.ssl_context.set_alpn_protocols(["h2", "http/1.1"])
+ 
+-        try:
+-            self.ssl_context.set_npn_protocols(["h2", "http/1.1"])
+-        except NotImplementedError:
+-            pass
+-
+         self.address = None
+         self.homeserver = None
+         self.client = None  # type: Optional[HttpClient]
diff --git a/net-im/weechat-matrix/weechat-matrix-0.3.0.ebuild b/net-im/weechat-matrix/weechat-matrix-0.3.0.ebuild
index c5b18de..a89fb25 100644
--- a/net-im/weechat-matrix/weechat-matrix-0.3.0.ebuild
+++ b/net-im/weechat-matrix/weechat-matrix-0.3.0.ebuild
@@ -36,8 +36,10 @@ DEPEND="
 RDEPEND="${DEPEND}"
 BDEPEND=""
 
+PATCHES=( "${FILESDIR}/${P}-ssl_set_npn_protocols.patch" )
+
 src_install() {
 	python_domodule matrix
 	exeinto /usr/lib/weechat
-	newexe main.py matrix.py
+	newexe main.py ${PN}.py
 }